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1. Carlier PR, Du D, Han YF, Liu J, Perola E, Williams ID, Pang YP. Dimerization of an inactive fragment of Huperzine A produces a drug with twice the potency of the natural product. Angew Chem Ont Ed. 39:1775-7.
2. Han Y, Wu D, Xiao X, Chen PM, Chung W, Lee NT, Pang Y, Carlier PR. Protection against ischemic injury in primary cultured astrocytes of mouse cerebral cortex by bis(7)-tacrine, a novel anti-Alzheimer's agent. Neurosci Lett. 288:95-8.
3. Zeng XM, Chan CM, Weng LT, Li L. Surface characterization and quantitative study of poly(4-vinyl phenol) and poly(4-vinyl pyridine) blends by XPS and ToF-SIMS. Polymer 41:8321-29.
4. Liu S, Weng LT, Chan CM, Lin L, Ho KC, Jiang M. Surface characterization of poly(styrene-co-p-hexafluorohydroxyisopropyl-alpha-methyl styrene) copolymers by ToF-SIMS, XPS and contact angle measurements. Surf Interface Analy. 29:500-7
5. Wang Z, Chen G. Heat and mass transfer in batch fluidized drying porous particles. Chemical Engineering Science 55:1857-69
6. Wang Z, Chen G. Theoretical study of fluidized bed drying with microwave heating. Industrial Engineering and Chemistry Research 59:775-82
7. Han YF, Carlier PR, Tang XC, Pang YP, Chen KX. East meets west in the search for Alzheimer's therapeutics-from huperzine A to novel dimeric acetylcholinesterase inhibitors", In: TCM Research and Development: Reviews by BRI Visiting Scholars (1997 -1999). Ed. Ip N, Science Press, pp162-71.
8. Liu J, Ho W, Lee NT, Carlier PR, Pang YP, Han YF. Bis(7)-tacrine, a novel acetylcholinesterase inhibitor, reverses AF64F-induced deficits in navigational memory in rats. Neuroscience Letters 282:165-8.
9. Pan SY, Han YF. Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine. Acta Pharmacol Sin. 21:124-30.
10. Wu DC, Xiao XQ, Ng AK, Chen PM, Chung W, Lee NT, Carlier PR, Pang YP, Yu AC, Han YF. Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor. Neurosci Lett. 288:95-8.
11. Wu DC, Yu YP, Lee NT, Yu AC, Wang JH, Han YF. The expression of Cdk5, p35, p39, and Cdk5 kinase activity in developing, adult, and aged rat brains. Neurochem Res. 25:923-9.
12. Xiao XQ, Lee NT, Carlier PR, Pang Y, Han YF. Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells:
comparison with tacrine. Neurosci Lett. 290:197-200.
13. Feng Z, Hong J, Qi Q, Han Y, Wilson B, Iadarola M, Tiao N, Bing G. Cloning and expression of MP13 gene from rat hippocampus, a new factor related to guanosine triphosphate regulation. Neurosci Lett. 296:129-32.
14. Xiao XQ, Wang R, Han YF, Tang XC. Protective effects of huperzine A on beta-amyloid(25-35) induced oxidative injury in rat pheochromocytoma cells. Neurosci Lett. 286:155-8.
15. Wang LM, Han YF, Tang XC. Huperzine A improves cognitive deficits caused by chronic cerebral hypoperfusion in rats. Eur J Pharmacol. 398:65-72.
16. Lee MH, Hsing I-M, Lao AIK, Carles MC. A miniaturized DNA amplifier: its application in traditional Chinese medicine. Analytical Chemistry 72:4242-7.
17. Cheung WM, Chu PW, Lung CH, Ip NY. Expression of retinoid receptors during the retinoic acid-induced neuronal differentiation of human embryonal carcinoma cells. J Neurochem. 75:34-40.
18. Cheung WM, Hui WS, Chu PW, Chiu SW, Ip NY. Ganoderma extract activates MAP kinases and induces the neuronal differentiation of rat pheochromocytoma PC12 cells. FEBS Lett. 486:291-296.
19. Tang H, Cheung WM, Ip FC, Ip NY. Identification and characterization of differentially expressed genes in denervated muscle. Mol Cell Neurosci. 16:127-40.
20. Tang H, Fu WY, Ip NY. Altered expression of tissue-type plasminogen activator and type 1 inhibitor in astrocytes of mouse cortex following scratch injury in culture. Neurosci Lett. 285:143-6.
21. Ip FC, Glass DG, Gies DR, Cheung J, Lai KO, Fu AK, Yancopoulos GD, Ip NY. Cloning and characterization of muscle-specific kinase in chicken. Mol Cell Neurosci. 16:661-73.
22. Ip FC, Chung SS, Fu WY, Ip NY. Developmental and tissue-specific expression of DEAD box protein p72. Neuroreport. 11:457-62.
23. Lao A, Thomas T, Hsing I-M, Ip NY. Precise Temperature Control of Microfluidic Chamber for Gas and Liquid Phase Reactions. Sensors and Actuators 84:11-17.
24. Xie P, Chan FS, Ip NY, Leung MF. Induction of TrkA expression by differentiation inducers in human myeloid leukemia KG-1 cells. Leuk Lymphoma. 36:595-601.
25. Kung SD, Wong JT, Ip NY. Biotechnology finds its way to Hong Kong. International Journal of Biotechnology. 2:355-63.
26. Lenigk R, Lam E, Lai A, Wang H, Han Y, Carlier P, Renneberg R. Enzyme biosensor for studying therapeutics of Alzheimer's disease. Biosensors and Bioelectronics 15:541-7.
27. Sucher NJ, Deitcher DL, Baro DJ, Warrick RM, Guenther E. Genes and channels: patch/voltage-clamp analysis and single-cell RT-PCR. Cell Tissue Res. 302:295-307.
28.

Lipton SA, Choi Y-B, Sucher NJ, Chen HS-V. Neuronal protection by nitric oxide-related species. In: Nitric Oxide in the Eye, Ed: Kashii S, Honda H, Akaike A, Springer-Verlag, Tokyo.

29. Choi RCY, Siow LN, Zhu SQ, Tsim KWK. The cAMP-dependaent protein kinase mediates the expression of AChE in chick myotubes. NeuroReport 11:801-6.
30. Cai ZH, Li P, Gao SL, Dong TTX, Tsim KWK. Physiology and biochemical analysis of cultured F. puqiensis during bulb organogenesis. J. Wuhan Botanical Research 17:314-318.
31. Cai ZH, Li P, Dong TTX, Tsim KWK. Molecular biological identification of the Chinese drug Beimu (Bulbus fritillariae). Acta Pharma. Sinica 35:309-12.
32. Wan DCC, Choi RCY, Siow N, Tsim KWK. The promoter of human acetycholinesterase is activated by a cyclic adenosine 3',5'-monophosphoate-dependent pathway in cultured NG108-15 neuroblastoma cells. Neurosci Lett. 288:81-5.
33. Ma XQ, Duan JA, Zhu DY, Dong TTX, Tsim KWK. Species identification of Radix Astragali (Huangqi) by DNA sequence of its 5S-rRNA spacer domain. Phytochemistry 54:363-8.
34. Ma XQ, Dong TTX, Tsim KWK. Active compounds determination of Crocus sativus and its related species by HPCE. J Pharm Practice 42: 213-217.
35. Ma XQ, Duan JA, Zhu DY, Dong TTX, Tsim KWK. Chemical comparison of Astragali Radix (huangqi) from different regions of China. Natural Medicines 54:213-8.
36. Wang YQ, Zhou KY, Xu LS, Tsim KWK. The present situation and application of the molecular identification of Chinese medicinal materials. Prog Pharmaceutical Sci. 23:193-198.
37. Wang Y, Zhou K, Xu L, Dong TTX, Tsim KWK. Authentication of an animal crude drug, Zaocyc, by diagnostic PCR. Biol Pharm Bull. 23:585-588.
38. Li SP, Li P, Dong TTX, Tsim KWK. Implication and prospect of bio-chip on the identification of traditional Chinese medicine. World Science & Technology-Modernization of Traditional Chinese Medicine 2:15-18.
39. Wang X, Ching YP, Lam WH, Qi Z, Zhang M, Wang JH. Identification of a common protein association region in the neuronal Cdk5 activator. J Biol Chem. 275:31763-9.
40. Ching YP, Qi Z, Wang JH. Cloning of three novel neuronal Cdk5 activator binding proteins. Gene 242:285-94.
41. New DC, Wong YH, Wong JT. Cloning of a novel G protein-coupled receptor from the sea anemone nervous system. Biochem Biophys Res Commun. 271:761-9.
42. Xiang Y, Wong W-KR., Ma MC, Wong RSC. Agrobacterium-mediated transformation of Brassica campestris ssp. Parachinensis with synthetic Bacillus thuringiensis cry1Ab and cry1Ac genes. Plant Cell Reports 19:251-6.
43. Chan AS, Wong YH. Regulation of c-Jun N-terminal kinase by the ORL1 receptor through multiple G proteins. J Pharmacol Exp Ther. 295:1094-100.
44. Yung LY, Tsim KW, Pei G, Wong YH. Immunoglobulin G1 Fc fragment-tagged human opioid receptor-like receptor retains the ability to inhibit cAMP accumulation. Biol Signals Recept. 9:240-7.
45. Chan JS, Lee JW, Ho MK, Wong YH. Preactivation permits subsequent stimulation of phospholipase C by Gi-coupled receptors. Mol Pharmacol. 57:700-8.
46. Mody SM, Ho MKC, Joshi SA, Wong YH. Incorporation of Gaz-specific sequence at the carboxyl terminus increases the promiscuity of Ga16 toward Gi-coupled receptors. Mol Pharmaccol. 57:13-23.
47. Ho MK, Chan JS, Yung LY, Wong YH. The effect of protein kinase C activation on Gz-mediated regulation of type 2 and 6 adenylyl cyclases. Biol Signals Recept. 9:21-8.
48. Ho MK, Wong YH. The amino terminus of Gaz is required for receptor recognition, whereas its a4/b6 loop is essential for inhibition of adenylyl cyclase. Mol Pharmacol. 58:993-1000.
49. Tso PH, Yung LY, Wong YH. Regulation of adenylyl cyclase, ERK1/2, and CREB by Gz following acute and chronic activation of the d-opioid receptor. J Neurochem. 74:1685-93.
50. Tso PH, Wong YH. Gz Can mediate the acute actions of m- and k-opioids but is not involved in opioid-induced adenylyl cyclase supersensitization. J Pharmacol Exp Ther. 295:168-176.
51. Tso PH, Wong YH. Deciphering the role of Gi2 in opioid-induced adenylyl cyclase supersensitization. Neuroreport. 11:3213-7.
52. Belcheva MM, Wong YH, Coscia CJ. Evidence for transduction of m- but not k-opioid modulation of extracellular signal-regulated kinase activity by Gz and G12 proteins. Cell Signal. 12:481-9.
53. Law PY, Wong YH, Loh HH. Molecular mechanisms and regulation of opioid receptor signaling. Annu Rev Pharmacol Toxicol. 40:389-430. Review.
54. Antonelli V, Bernasconi F, Wong YH, Vallar L. Activation of B-Raf and regulation of the mitogen-activated protein kinase pathway by the Goa chain. Mol Biol Cell. 11:1129-42.
55. Puri PL, Wu Z, Zhang P, Wood LD, Bhakta KS, Han J, Feramisco JR, Karin M, Wang JY. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. Genes Dev. 14:574-84.
56. Wu Z, Woodring PJ, Bhakta KS, Tamura K, Wen F, Feramisco JR, Karin M, Wang JY, Puri PL. p38 and extracellular signal-regulated kinases regulate the myogenic program at multiple steps. Mol Cell Biol. 20:3951-64.
57. Xu Q, Wu Z. The insulin-like growth factor-phosphatidylinositol 3-kinase-Akt signaling pathway regulates myogenin expression in normal myogenic cells but not in rhabdomyosarcoma-derived RD cells. J Biol Chem. 275:36750-7.
58.
Hui KM, Wang XH, Xue H. Interaction of flavones from the roots of Scutellaria baicalensis with the benzodiazepine site. Planta Med. 66:91-3.
59. Wang P, Zhang Q, Tochio H, Fan J-S, Zhang M. Formation of a native-like beta-hairpin finger structure of a peptide from the extended PDZ domain of neuronal nitric oxide synthase in aqueous solution. Eur. J. Biochem. 267:3116-22.
60. Tochio H, Hung F, Li M, Bredt DS, Zhang M. Solution structure and backbone dynamics of the second PDZ domain of postsynaptic density-95. J Mol Biol. 295:225-37.
61. Xia Y, Kong X, Ip NY, Zhu G. A J-multiplied HMQC (MJ-HMQC) experiment for measuring (3)J(HNHalpha) coupling constants. J Magn Reson. 146:228-31.
62. TCM Research and Development: Reviews by BRI Visiting Scholars (1997 -1999), ed. BRI, Science Press.



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